ECOTOXICOLOGIA AQUATICA PDF

Numerous and frequently-updated resource results are available from this WorldCat. Please choose whether or not you want other users to be able to see on your profile that this library is a favorite of yours. Finding libraries that hold this item You may have already requested this item.

Author:Bataur Kisho
Country:Mayotte
Language:English (Spanish)
Genre:Automotive
Published (Last):28 November 2019
Pages:123
PDF File Size:12.14 Mb
ePub File Size:12.48 Mb
ISBN:866-5-28701-404-7
Downloads:99523
Price:Free* [*Free Regsitration Required]
Uploader:Grozragore



Anticancer drugs are designed to inhibit tumor cell proliferation by interacting with DNA and altering cellular growth factors. When released into the waterbodies of municipal and hospital effluents these pharmaceutical compounds may pose a risk to non-target aquatic organisms, due to their mode of action cytotoxic, genotoxic, mutagenic and teratogenic.

The present study aimed to assess the ecotoxicological potential of the alkylating agent cisplatin CisPt to the polychaete Nereis diversicolor, at a range of relevant environmental concentrations i. Significant burrowing impairment occurred in worms exposed to the highest CisPt concentration ngPtL -1 along with neurotoxic effects.

Furthermore, LPO levels also increased. Results showed that the mode of action of cisplatin may pose a risk to this aquatic species even at the range of ngL This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search.

Advanced Clipboard. Create file Cancel. Email citation To:. Format: Summary Summary text Abstract Abstract text. Send email Cancel. Add to Collections Create a new collection Add to an existing collection. Name your collection: Name must be less than characters. Choose a collection: Unable to load your collection due to an error Please try again. Add Cancel. Add to My Bibliography My Bibliography. Unable to load your delegates due to an error Please try again.

Your saved search Name of saved search:. Search terms:. Test search terms. Would you like email updates of new search results?

Email: change. Frequency: Monthly Weekly Daily. Which day? Send at most: 1 item 5 items 10 items 20 items 50 items items items. Send even when there aren't any new results. Optional text in email:. Save Cancel. Create a file for external citation management software Create file Cancel.

Full-text links Cite Favorites. Abstract Anticancer drugs are designed to inhibit tumor cell proliferation by interacting with DNA and altering cellular growth factors. Similar articles Effects of mixtures of anticancer drugs in the benthic polychaete Nereis diversicolor. Environ Pollut. Epub Jun 6. PMID: Environmental relevant levels of the cytotoxic drug cyclophosphamide produce harmful effects in the polychaete Nereis diversicolor. Fonseca TG, et al. Sci Total Environ.

Epub May 1. Bioavailability, oxidative stress, neurotoxicity and genotoxicity of pharmaceuticals bound to marine sediments. The use of the polychaete Hediste diversicolor as bioindicator species. Maranho LA, et al. Environ Res. Epub Sep 7. Sun F, Zhou Q. Sun F, et al. PMID: Review. Expanding the ecotoxicological toolbox: the inclusion of polychaete reproductive endpoints. Lewis C, Watson GJ. Lewis C, et al. Mar Environ Res. Epub Aug Show more similar articles See all similar articles.

Cited by 1 article Organotropism and biomarker response in oyster Crassostrea gigas exposed to platinum in seawater. Abdou M, et al. Environ Sci Pollut Res Int. Epub Oct MeSH terms Animals Actions. DNA Damage Actions. Oxidative Stress Actions. Substances Antineoplastic Agents Actions. Water Pollutants, Chemical Actions. Cisplatin Actions. Full-text links [x] Elsevier Science. Copy Download.

ANNE CAIN PAWPRINTS PDF

Ecotoxicological Assessment of the Anticancer Drug Cisplatin in the Polychaete Nereis Diversicolor

Anticancer drugs are designed to inhibit tumor cell proliferation by interacting with DNA and altering cellular growth factors. When released into the waterbodies of municipal and hospital effluents these pharmaceutical compounds may pose a risk to non-target aquatic organisms, due to their mode of action cytotoxic, genotoxic, mutagenic and teratogenic. The present study aimed to assess the ecotoxicological potential of the alkylating agent cisplatin CisPt to the polychaete Nereis diversicolor, at a range of relevant environmental concentrations i. Significant burrowing impairment occurred in worms exposed to the highest CisPt concentration ngPtL -1 along with neurotoxic effects.

HARDEGREE SYMBOLIC LOGIC PDF

Ecotoxicologia aquática : princípios e aplicações

.

Related Articles